Our study highlighted that CirS and increasing number of components associated with CMM. The combination of CirS and IADL disability was significantly associated with new-onset CMM. In addition, IADL disability mediated the effect of CirS on the progression to CMM, accounting for 8.37% of the total effect. Our findings provided new insights into prevention of CMM.
Fang et al. (Mon,) studied this question.