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December 6, 2025Clinical Case Reports2 citationsOpen Access

Systemic Lupus Erythematosus With Catastrophic APS and Libman–Sacks Endocarditis in a Patient With Autoimmune Hemolytic Anemia: A Case Report

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SMShabnam Danaei Mehrabad

Key Points

  • SLE led to multiple complications, including thrombotic events and endocarditis.
  • This case emphasizes the crucial role of immunosuppressive therapy in SLE-related APS.
  • Assessment of antiphospholipid syndrome is essential in SLE patients with unusual symptoms.
  • Rapid anticoagulation may prevent severe outcomes in patients with SLE and APS.

Abstract

ABSTRACT Systemic lupus erythematosus (SLE) can lead to antiphospholipid syndrome (APS) and catastrophic APS (CAPS), causing severe thrombotic events. This case of autoimmune hemolytic anemia (AIHA) with stroke and Libman–Sacks endocarditis highlights the need for APS evaluation and shows that prompt anticoagulation and immunosuppressive therapy are crucial in such cases.

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Cite This Study

Shabnam Danaei Mehrabad (2025) studied this question.

synapsesocial.com/papers/69337cceb3f947a0a1259bf3https://doi.org/10.1002/ccr3.71552
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