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December 6, 2025Premier journal of science.Open Access

CAR-T Cell Therapy: Revolutionizing Cancer Treatment and its Implications for Future Therapeutic Strategies: A Review

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Authors

SDS DwivediGanesh Shankar Vidyarthi Memorial Medical CollegeHCHerschel A. CarpenterMayo Clinic

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Implication

Review highlights CAR-T cell therapy's efficacy in hematological malignancies, suggesting enhanced personalized immunotherapies through gene editing.

Key Points

  • CAR-T cell therapy shows promise in treating cancer, particularly for relapsed hematological malignancies.
  • Notable challenges include cytokine release syndrome and issues with manufacturing and efficacy in solid tumors.
  • The review evaluates FDA-approved CAR-T therapies like CD19 and BCMA, indicating high response rates and ongoing advancements.
  • Integration of gene editing could enhance CAR-T therapies, yet safety, accessibility, and cost must be balanced.

Cite This Study

Dwivedi et al. (2025) studied this question.

synapsesocial.com/papers/69337cdbb3f947a0a1259efdhttps://doi.org/10.70389/pjs.100162
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