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December 6, 2025Critical Care8 citationsOpen Access

Site-specific complications of central venous catheterization under systematic ultrasound guidance: a target trial emulation revisiting the 3SITES study

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AGAntoine GavoilleMTMarie ThuongMRMichel Ramakers

Key Points

  • Subclavian access in central venous catheterization results in a lower thrombotic risk, enhancing patient safety.
  • Reduced infectious risk and no increase in mechanical complications support subclavian access for intensive care units.
  • The analysis revisited the findings from the 3SITES study, emphasizing the benefits of ultrasound guidance.
  • These findings may influence catheterization practices, highlighting the importance of site selection for improving outcomes.

Abstract

Assuming universal real-time ultrasound-guided central venous catheterization, subclavian access retains lower infectious and thrombotic risk without an observed increase in mechanical complications, supporting its preferential use in intensive care units.

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Cite This Study

Gavoille et al. (2025) studied this question.

synapsesocial.com/papers/69337cdbb3f947a0a125a032https://doi.org/10.1186/s13054-025-05747-3
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