Cereglide‐92 Catheter for Aspiration Thrombectomy in Right Transverse Sinus Thrombosis

Introduction Venous thrombectomy is considered in patients with extensive clot burden, those who fail to improve with anticoagulation, or when anticoagulation is contraindicated. Endovascular aspiration techniques provide a means to rapidly reduce thrombus load and restore venous outflow in such cases. The Cereglide‐92 catheter (Johnson & Johnson) is a large‐bore aspiration device originally designed for large vessel occlusion strokes. We report a case in which Cereglide‐92 was successfully used for aspiration of a venous thrombus from the right transverse sinus (RTS). Case Description A 64‐year‐old male with multiple intracranial lesions, possible metastasis, presented with slurred speech and was found to have a right parietotemporal intracerebral hemorrhage with vasogenic edema. He underwent a right frontal burr hole biopsy of his lesion. During admission, he developed intermittent left lower face twitching. Post‐biopsy computed tomography (CT) scan demonstrated hyper attenuation of the RTS (Fig 1(A)) and a CT venogram confirmed RTS thrombosis. He was started on Levetiracetam for seizures and after multidisciplinary discussion, anticoagulation with Heparin drip was initiated, weighing the benefit against the risk of bleeding into his intracranial lesions. Despite anticoagulation, he developed left upper and lower extremity weakness, slurred speech and right gaze deviation. Repeat CT scan showed progression of the RTS thrombosis. He underwent emergent venous thrombectomy via a right femoral approach. Using Cereglide‐92 catheter, three passes of aspiration were performed at the confluence and RTS, achieving recanalization. (Fig 2). The patient improved clinically and a CT scan two days later showed resolution of RTS hyper attenuation (Fig1 (B)). Conclusion This case demonstrates the feasibility of using the Cereglide‐92 catheter for venous thrombectomy, expanding potential applications beyond acute ischemic stroke. The catheter's large inner diameter enabled effective thrombus aspiration, while the co‐packaged innerglide catheter facilitated smooth Cereglide‐92 advancement and allowed contrast injections between passes, supporting efficient multiple aspiration attempts.