In vitro model demonstrates electrophysiological responses in neuron-keratinocyte interactions, suggesting advancements in sensory response understanding.
This study introduces a human-relevant in vitro model using iPSC-derived sensory neurons and keratinocytes in MEA-integrated microfluidic chips. Neurons expressed nociceptor markers, showed TRPV activity, and formed contacts with keratinocytes....
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Martinez et al. (2025) studied this question.
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