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December 8, 2025npj Parkinson s DiseaseOpen Access

Subitem-level multi-scale assessment and machine learning for three-class cognitive status classification in Parkinson’s disease

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Authors

RYRwei‐Ling Yu

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Overview

Machine learning identifies cognitive status in Parkinson's disease, suggesting better decision support for clinical care.

Key Points

  • Cognitive impairments affect people with Parkinson's disease, leading to a need for accurate classification.
  • Machine learning techniques supported robust classification across cognitive subgroups, achieving an area under the curve above 0.85.
  • A two-stage model combining multilayer perceptron and feature selection was applied using data from the Parkinson's Progression Markers Initiative.
  • The findings imply that better classification can enhance decision support in clinical workflows, requiring additional external validation.

Cite This Study

Rwei‐Ling Yu (2025) studied this question.

synapsesocial.com/papers/693624ba4fa91c937236c9e0https://doi.org/10.1038/s41531-025-01218-2
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