PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
December 8, 2025Interventional NeuroradiologyOpen Access

Epigenetic mechanisms in aneurysm formation, growth, and rupture: A systematic review

View Full Paper
Ask AI
Bookmark
Share

Authors

IMIrina‐Mihaela MatacheGPGennadii Piavchenko

Discussion

Loading...

Member takes

Overview

Systematic review reveals epigenetic mechanisms influence aneurysm rupture in intracranial aneurysms, indicating a need for standardized methods.

Key Points

  • Aneurysm rupture underscores the importance of understanding epigenetic mechanisms in pathogenesis.
  • Key findings show DNA methylation and histone modification play critical roles in aneurysm development.
  • Systematic review of 1019 studies identified significant heterogeneity in methodologies and targets.
  • Standardized approaches may enable better reproducibility in research on aneurysm pathogenesis.

Cite This Study

Matache et al. (2025) studied this question.

synapsesocial.com/papers/693624c34fa91c937236cbddhttps://doi.org/10.1177/15910199251391864
View Full Paper
Ask AI
Bookmark
Share