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December 8, 2025Blood

Clinician-assessed eastern cooperative oncology group performance status vs. patient-reported health-related quality of life: Insights from malignant lymphoma

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Authors

WQWei QinWCWendong ChenFCFangping Chen

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Overview

Analysis shows a strong link between clinician-assessed ECOG-PS and patient-reported HRQoL in lymphoma, suggesting vital implications for treatment.

Key Points

  • To evaluate the relationship between clinician-assessed ECOG-PS and patient-reported HRQoL in lymphoma patients.
  • Patients with lymphoma recruited from a tertiary hospital in China
  • ECOG-PS assessed by two clinicians
  • HRQoL self-reported using the EuroQoL-5 Dimensions-5 Levels questionnaire
  • Statistical comparisons made using ANOVA and Chi-squared test
  • Relationship evaluated through regression analysis
  • Significant variation in EQ-5D-5L utility scores across ECOG-PS ratings (P < 0.001)
  • EQ-VAS scores also significantly varied by ECOG-PS ratings (P < 0.001)
  • ECOG-PS strongly correlates with HRQoL dimensions (all P < 0.001)
  • Worse ECOG-PS predicts lower patient-reported HRQoL (P < 0.001)

Cite This Study

Qin et al. (2025) studied this question.

synapsesocial.com/papers/69362f3d4fa91c937236d4e1https://doi.org/10.1182/blood-2025-4509
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