Impact of recipient sociodemographic factors on allogeneic transplant conditioning intensity and survival outcomes in myeloid malignancies: A secondary analysis of CIBMTR data
Multivariable analysis reveals age influences conditioning intensity for allogeneic transplant in myeloid malignancies, suggesting clinical factors guide treatment choices.
Key Points
To assess the impact of sociodemographic factors on conditioning intensity and survival outcomes in allogeneic transplantation for myeloid malignancies.
Analyzed data from the CIBMTR dataset involving 1675 patients with myeloid malignancies.
Examined the association of sociodemographic factors with conditioning intensity using logistic regression.
Survival outcomes assessed through Kaplan-Meier and log-rank tests.
Age was significantly associated with the choice of conditioning intensity for allogeneic HCT.
Higher progression free survival observed for patients receiving myeloablative conditioning compared to reduced intensity conditioning.
Sociodemographic factors did not significantly affect survival outcomes in this dataset.