Improving the efficacy of functional endoscopic sinus surgery in chronic rhinosinusitis with nasal polyps through the combination of budesonide infiltration therapy

Jing-Jing Cun; Jianhui Wu; Qian Pan; Xin Li; Qi N. Cui; Zhong Pan; Rong Chen; Minyi Fu

doi:10.1186/s12893-025-03430-6

December 13, 2025BMC SurgeryOpen Access

Improving the efficacy of functional endoscopic sinus surgery in chronic rhinosinusitis with nasal polyps through the combination of budesonide infiltration therapy

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Key Points

To assess how budesonide infiltration therapy affects outcomes in functional endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps.
Combination of functional endoscopic sinus surgery and budesonide infiltration therapy
Evaluation of olfactory recovery and nasal function
Study conducted in patients with chronic rhinosinusitis and nasal polyps
Improved olfactory recovery after surgery
Enhanced nasal function reported
Increased overall clinical efficacy
Potential reduction in postoperative complications

Discussion

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Implication

Budesonide infiltration improves clinical efficacy and nasal function in chronic rhinosinusitis with polyps, indicating a safe adjunctive treatment.

Abstract

FESS combined with intraoperative budesonide infiltration therapy might improve olfactory recovery, nasal function, and overall clinical efficacy, while potentially reducing postoperative complications in CRSwNP patients, suggesting it could be a safe and effective adjunctive intervention.

Cite This Study

Cun et al. (2025) studied this question.

synapsesocial.com/papers/694018f82d562116f28f5d80 https://doi.org/10.1186/s12893-025-03430-6

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