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December 12, 2025Experimental and Clinical Endocrinology & Diabetes

Association of fibrosis index-4 (FIB-4) with chronic vascular complications of type 2 diabetes mellitus

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Authors

ΝΠΝικόλαος ΠαπάναςEGEvanthia GouveriTPTheodoros Panou

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Overview

Observational study links higher FIB-4 score with more chronic kidney disease, neuropathy, and vascular issues in type 2 diabetes.

Key Points

  • The study aims to explore the association between FIB-4 scores and chronic vascular complications in type 2 diabetes mellitus.
  • Examined 550 adults with type 2 diabetes mellitus
  • Calculated FIB-4 scores and recorded chronic vascular complications
  • Compared participants with FIB-4 > 1.3 and ≤ 1.3
  • Participants with FIB-4 > 1.3 had significantly higher rates of chronic kidney disease and peripheral neuropathy
  • Observed increased odds ratios for stroke and coronary artery disease in those with higher FIB-4 scores
  • Peripheral neuropathy severity was linked to elevated FIB-4 scores

Cite This Study

Παπάνας et al. (2025) studied this question.

synapsesocial.com/papers/694019192d562116f28f6744https://doi.org/10.1055/a-2765-6480
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