A diagnostic model shows good robustness and accuracy for identifying asymptomatic neurosyphilis in HIV patients, indicating its potential for clinical use without lumbar puncture.
The diagnostic model achieved an AUC greater than 70 for detecting ANS in PLWH, with good robustness confirmed by calibration and DCA, as well as subgroup analyses. This model can assist clinicians in identifying ANS in PLWH without requiring LP.
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Guan et al. (2025) studied this question.
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