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December 9, 2025Future Medicinal Chemistry

Purine derivatives as potent anticancer agents: a comprehensive review

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Authors

FFF. FAROOQUIAKAbdul Rahman KhanMKMusarrat Abbas Khan

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Overview

Comprehensive review shows purine derivatives improve efficacy against cancer, targeting drug resistance pathways in treatment.

Key Points

  • To review the advances in purine derivatives as anticancer agents and their mechanistic roles.
  • Comprehensive review of recent literature on purine derivatives and their applications in cancer therapy.
  • Analysis of synthetic purine analogues and their clinical approvals.
  • Discussion of multitargeted approaches and their impact on drug efficacy.
  • Purine derivatives show promising efficacy as anticancer agents in various studies.
  • Purine-based hybrid molecules are effective in overcoming drug resistance.
  • Integration of purine scaffolds with heterocyclic frameworks enhances therapeutic outcomes.

Cite This Study

FAROOQUI et al. (2025) studied this question.

synapsesocial.com/papers/69401ef02d562116f28f9717https://doi.org/10.1080/17568919.2025.2594966
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