Adaptation and Validation of the Fear of Blistering Disease Recurrence Inventory

Introduction: Autoimmune blistering diseases (AIBDs) are severe, life-threatening conditions known for their debilitating physical and psychological impacts. The conditions also have a high rate of recurrence, leading to patient distress. This study adapted and validated a widely-used measure, the Fear of Cancer Recurrence Inventory – Short Form, for use with patients with AIBDs. Methods: Adult volunteers (n=219) with AIBD completed an anonymous online questionnaire battery. In addition to the Fear of Blistering Disease Recurrence Inventory – Short Form (FBDRI-SF), participants provided demographic and disease course information and completed the ultra-brief Patient Health Questionnaire for Depression and Anxiety (PHQ-4). Results: The FBDRI-SF demonstrated excellent psychometric properties. Scores on the FBDRI-SF were associated with disease course, depression, and anxiety, suggesting that it a valid indicator of clinically significant psychological distress. Conclusion: The FBDRI-SF is a brief and useful screen to identify AIBD patients likely to benefit from psychological evaluation and support.