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December 8, 2025Transfusion0 citationsOpen Access

Impact of Pathogen-Reduced Cryoprecipitate on Fibrinogen Repletion in Surgical Patients

Implementation of pathogen reduced cryoprecipitate for surgical services: A retrospective review of blood product utilization and fibrinogen repletion

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Authors

JNJoshua NicholasAGAnna Graber‐NaidichTPTho D. Pham

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Overview

Retrospective cohort study highlights reduced turnaround times for plasma transfusion in surgical patients with hypofibrinogenemia.

Key Points

  • Cryoprecipitate implementation reduces turnaround times for transfusion, improving efficiency.
  • Plasma fibrinogen increment was lower post-implementation, but no overall change in transfusion rates occurred.
  • Retrospective cohort design assessed adult surgical patients receiving cryoprecipitate over 18 months total.
  • Implies improved efficiencies in transfusion practices during surgical procedures may not significantly impact fibrinogen levels.

Cite This Study

Nicholas et al. (2025) studied this question.

synapsesocial.com/papers/694020d72d562116f28fa73fhttps://doi.org/10.1111/trf.70030
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