Observational analysis reveals pH-triggered DNA delivery in living cells, suggesting nanopipettes enable targeted genetic manipulation.
Here, we present i-motif-functionalized glass nanopipettes that enable pH-triggered DNA release into single living cells. Acid-induced folding of the i-motif drives complementary strand dissociation through ~80 nm tip with minimal...
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Yu-zheng et al. (2025) studied this question.
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