Analysis reveals expanded T cells associated with disease activity in granulomatosis with polyangiitis, suggesting potential therapeutic targets.
cTph cells are expanded and exhibit an activated, pro-inflammatory profile with a cTph2-skewed distribution in active GPA-patients. Their association with disease activity may support a potential role in disease pathogenesis and highlight their potential as therapeutic targets, warranting further investigation.
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Inrueangsri et al. (2025) studied this question.
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