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December 6, 2025BMC Cancer2 citationsOpen Access

Identification and validation of key biomarkers for chemoresistance in oral squamous cell carcinoma

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QLQiong LiQGQianqian GaoWZWenjuan Zhang

Key Points

  • Cisplatin resistance indicates a need for effective biomarkers in treatment strategies.
  • Key prognostic indicator DUSP3 identified for enhancing patient care.
  • Multi-omics approach explores biomarkers linked to chemoresistance in OSCC.
  • The nomogram developed may support precision oncology decisions for affected patients.

Abstract

This study provides a comprehensive multi-omics-based framework for understanding cisplatin resistance in OSCC. DUSP3 was identified as a key prognostic indicator, and the proposed nomogram may enhance precision oncology efforts for cisplatin-resistant OSCC patients.

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Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/694020f72d562116f28fb409https://doi.org/10.1186/s12885-025-15395-z
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