Preservation of adaptive immunity is associated with survival in invasive fungal sinusitis

Iris Lee; Sonam Verma; John S. Schneider; Nyssa Fox Farrell; Peggy L. Kendall; Lauren T. Roland

doi:10.1016/j.amjoto.2025.104779

December 4, 2025American Journal of OtolaryngologyOpen Access

Preservation of adaptive immunity is associated with survival in invasive fungal sinusitis

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Key Points

Survival is associated with adaptive immunity in invasive fungal sinusitis patients, indicating its crucial role.
Key evidence shows that preserving adaptive immunity correlates with improved survival rates.
Observational analysis highlights the importance of CD4 T cells as a potential biomarker in invasive fungal sinusitis cases.
These findings suggest that enhancing adaptive immunity may lead to better outcomes for patients with invasive fungal sinusitis.

Implication

Analysis identifies survival linked to adaptive immunity in invasive fungal sinusitis, implying potential as a biomarker.

Abstract

Future work includes the investigation of CD4 T cells as a biomarker for IFS survival and the study of T cell manipulation or stimulation in IFS patients.

Discussion

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Cite This Study

Lee et al. (2025) studied this question.

synapsesocial.com/papers/694023e92d562116f28fd5f1 https://doi.org/10.1016/j.amjoto.2025.104779

View Full Paper

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Preservation of adaptive immunity is associated with survival in invasive fungal sinusitis

Key Points

Implication

Abstract

Discussion

Cite This Study

Preservation of adaptive immunity is associated with survival in invasive fungal sinusitis

Key Points

Implication

Abstract

Discussion

Cite This Study

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