Observational analysis shows increased thyroid nodules in pregnant women exposed to radioiodine, indicating a need for targeted health strategies.
The significant risk of thyroid nodules associated with exposure in the third trimester indicates the presence of a vulnerable subgroup of pregnant women at the time of an accidental radioiodine release. Because of the strong correlation between gestational age and ¹³¹I dose in the fetal thyroid, the extent to which this excess risk is attributable to elevated ¹³¹I dose and/or radiosensitivity of the thyroid in later stage of fetal development remains unclear.
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Kukhta et al. (2025) studied this question.
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