This review demonstrates the role of hormone-related animal models in understanding endometriosis pathogenesis, indicating better options for therapeutic interventions.
Key Points
Endometriosis induces chronic pain and infertility, highlighting the need for effective therapeutic interventions.
Analysis included 158 studies evaluating sex steroid hormones and the hypothalamic-pituitary-gonadal axis.
Assessment of hormone-related animal models employed methods like autotransplantation and xenotransplantation.
Findings may support improved translational research for endometriosis therapies and awareness of model validity.