Pilot study finds biomarkers linked to drug-resistant epilepsy severity in dogs, suggesting immune response alterations.
Proteins with differential abundance studied here are associated with epilepsy due to their potential involvement in critical processes such as neuroprotection, inflammation, cell integrity, and immune response. The observed reduction in the abundance of these proteins in drug-resistant dogs suggests that disruptions in these processes may contribute to the severity of the condition and its resistance to treatment. Results from this pilot study warrant further study in a larger cohort.
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Kangas et al. (2025) studied this question.
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