Rapamycin-mediated inhibition of the mTOR pathway promotes tendon healing in a collagenase-induced achilles tendinopathy

Rapamycin effectively promotes Achilles tendon healing by inhibiting the collagenase-activated mTOR signaling pathway, particularly exhibiting potential in mitigating cartilage formation and improving histological recovery. Although its impact on biomechanical strength is limited, it may serve as a promising new strategy for treating tendinopathy.