Prognostic impact of Fusobacterium nucleatum in head and neck cancers: a meta-analysis of critical oncological outcomes

This meta-analysis suggests that Fusobacterium nucleatum abundance is significantly associated with better OS and DSS in patients with head and neck cancers. Fusobacterium nucleatum may be a potentially useful prognostic biomarker; however, this interpretation should be made with caution due to the limited evidence base, small number of studies, and residual heterogeneity. Taken together, further validation in large-scale, prospective studies is required and critical.