Retinomics: a window to multidisease prediction using retinal biomarkers from routine eye imaging

Retinomics universally enhanced disease prediction, with marked gains for conditions like cardiovascular and metabolic disorders. The onset of presbyopia (~ 50 years)-a common trigger for eye exams-aligns with escalating chronic disease risks, suggesting an opportunity to leverage routine eye care for broader health assessment. While requiring further validation, this approach demonstrates the potential to enhance health screening efficiency using existing ophthalmic infrastructure, offering particular value for resource-limited settings.