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November 26, 2025European journal of medical researchOpen Access

ddPCR-based profiling of plasma EV-miRNA identifies a noninvasive biomarker panel for tuberculosis

Jing Liang Yuchuan Zhao Jianming Hong Si-Lu Huang Xiaoyu Lai Ran Wei Jiawen Wang Xunxun Chen

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Abstract

This multigroup cohort study established a novel EV-miRNAs signature and demonstrated its clinical utility for TB staging and early detection.

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Cite This Study

Liang et al. (2025) studied this question.

synapsesocial.com/papers/694033f72d562116f2908496 https://doi.org/10.1186/s40001-025-03533-z

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1A novel nanosensor for in situ detection of EV-miR-107 enables noninvasive tuberculosis diagnosis and treatment monitoringOriginal Research · 2026
2Plasma miRNA signature for the diagnosis of pulmonary tuberculosis in symptomatic patientsCohort Study · 2026
3Diagnostic and differential diagnostic value of plasma extracellular vesicle-associated miRNAs in AIDS patients with tuberculosis and non-tuberculous mycobacterial infectionCase-Control Study · 2026
4A novel circulating miRNA panel for early differential diagnosis of pulmonary tuberculosis from lung cancer with similar radiographic presentations2025
5Human multiethnic radiogenomics reveals low-abundancy microRNA signature in plasma-derived extracellular vesicles for early diagnosis and molecular subtyping of pancreatic cancer2025 · 3 citations

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