Zero-shot SAM variants performed poorly, particularly on small or low-contrast structures. In contrast, adapted SAM models consistently outperformed CNNs, reaching DSC scores up to 0.90 (liver) and 0.80 (artery). Prompt-based interaction enables semi-automated, human-in-the-loop workflows, supporting clinical applicability.
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Fédérici et al. (2025) studied this question.
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