Observed perfusion decreases are consistent with PET evidence of cortical and thalamic downregulation during sleep and indicate suppression of brainstem arousal nuclei. These findings provide a detailed ASL characterization of cortical and brainstem perfusion changes during pharmacologically induced sleep, extending PET work and offering new insight into sleep-related arousal systems.
No takes yet. Share an insight, caveat, or question.
Örzsik et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: