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Nationwide genomic surveillance identifies spatial heterogeneity in dengue virus serotype 2 spread, suggesting adaptation needs.
Dengue remains a major public health challenge. In Costa Rica, we implemented nationwide genomic surveillance to track dengue virus serotype 2 cosmopolitan genotype emergence. Phylogenetic and eco-epidemiologic analyses revealed early detection, climate-driven spread, and spatial heterogeneity. Our findings underscore the need for integrated surveillance to guide adaptive responses to emerging arboviral threats.
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González-Elizondo et al. (2025) studied this question.
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