December 1, 2025Journal of obstetrics and gynaecology research

Short‐Term Indomethacin Use Reduces Preterm Premature Rupture of Membranes After Fetoscopic Laser Surgery for Twin‐to‐Twin Transfusion Syndrome

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Authors

MTMayu TachiharaToho University MTMayumi TakanoToho University JSJ. SakumaToho University

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Implication

This observational analysis finds indomethacin reduces pPROM after fetoscopic laser surgery in monochorionic diamniotic twins, suggesting improved postoperative management.

Key Points

Indomethacin effectively reduces preterm premature rupture of membranes within 14 days after fetoscopic laser surgery.
The IND group experienced 0% pPROM compared to 8.2% in the control group, with statistical significance (p = 0.022).
This observational analysis focused on monochorionic diamniotic twin pregnancies undergoing fetoscopic laser surgery for twins.
Indomethacin use may enhance postoperative management, indicating fewer adverse effects and reduced need for other tocolytic agents.

Cite This Study

Tachihara et al. (2025) studied this question.

synapsesocial.com/papers/6941adef0f5af7fd17df5f89 https://doi.org/10.1111/jog.70166

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Implication

This observational analysis finds indomethacin reduces pPROM after fetoscopic laser surgery in monochorionic diamniotic twins, suggesting improved postoperative management.

Short‐Term Indomethacin Use Reduces Preterm Premature Rupture of Membranes After Fetoscopic Laser Surgery for Twin‐to‐Twin Transfusion Syndrome

Discussion

Member takes

Implication

Key Points

Cite This Study

Short‐Term Indomethacin Use Reduces Preterm Premature Rupture of Membranes After Fetoscopic Laser Surgery for Twin‐to‐Twin Transfusion Syndrome

Discussion

Member takes

Implication

Key Points

Cite This Study

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