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September 10, 2007Bioinformatics29,245 citationsOpen Access

Clustal W and Clustal X version 2.0

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MLMark LarkinGBGordon BlackshieldsNBNigel P. Brown

Key Points

  • To update and rewrite the Clustal W and Clustal X multiple sequence alignment programs in C++ to support modern operating systems and facilitate future algorithm development.
  • Completely rewrote the source code for command-line Clustal W and graphical Clustal X in the C++ programming language.
  • Ported the software across modern Linux, Macintosh, and Windows operating systems.
  • Deployed the software as downloadable binaries and source code, as well as an online service hosted on the European Bioinformatics Institute (EBI) web server.
  • Successfully updated Clustal W and Clustal X to version 2.0 with full cross-platform compatibility across Linux, Mac OS, and Windows.
  • Enabled accessible web-based sequence alignment through the EBI web server alongside standalone executable packages.

Abstract

Abstract Summary: The Clustal W and Clustal X multiple sequence alignment programs have been completely rewritten in C++. This will facilitate the further development of the alignment algorithms in the future and has allowed proper porting of the programs to the latest versions of Linux, Macintosh and Windows operating systems. Availability: The programs can be run on-line from the EBI web server: http://www.ebi.ac.uk/tools/clustalw2. The source code and executables for Windows, Linux and Macintosh computers are available from the EBI ftp site ftp://ftp.ebi.ac.uk/pub/software/clustalw2/ Contact: clustalw@ucd.ie

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Cite This Study

Larkin et al. (2007) studied this question.

synapsesocial.com/papers/69430d5afe81bcbc98009924https://doi.org/10.1093/bioinformatics/btm404
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