Analysis reveals EGFR mutations and low expression of OLFM1 and BMP6 may influence recurrence in nonsquamous NSCLC.
RFS of patients categorized by BMP6 and OLFM1 expression status. A and B, RFS in cohort 2a, a real-world cohort of patients with pStage I nonsquamous NSCLC whose tumors were analyzed using PolyA sequencing. C and D, RFS in the cohort of patients with EGFR mutations extracted from cohort 1 and cohort 2. H&H, high and high indicates higher expression of both BMP6 and OLFM1; H&L, high and low indicates higher expression for either of the BMP6 and OLFM1 and lower expression for the other; L&L, low and low indicates lower expression of both BMP6 and OLFM1.
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Suda et al. (2025) studied this question.
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