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December 18, 2025

Supplementary Figure S3 from Low OLFM1 and BMP6 Expression Predicts Recurrence in Early-Stage Nonsquamous NSCLC with Pure Solid Tumor Appearance

Kenichi Suda Yukihiro Yoshida Hidenori Sato Shuta Ohara Akira Hamada Masaya Yotsukura Kouya Shiraishi Ryuji Hamamoto Yasutaka Chiba Takashi Kohno Yasushi Yatabe Shun‐ichi Watanabe Yasuhiro Tsutani Tetsuya Mitsudomi

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Key Points

To evaluate the relationship between OLFM1 and BMP6 expression and disease recurrence in early-stage nonsquamous NSCLC with solid tumor appearance.
Conducted mutational signature analysis on samples from recurrence and control groups.
Examined OLFM1 and BMP6 expression levels.
Analyzed the correlation with recurrence outcomes.
Identified key mutational signatures associated with recurrence in the examined groups.
Found that OLFM1 and BMP6 expression levels may serve as predictive markers for recurrence.

Implication

Mutational signature analysis reveals potential recurrence predictors in early-stage nonsquamous solid tumor NSCLC.

Abstract

Figure S3. Mutational signature analysis in Recurrence group (A) and in Control group (B).

Discussion

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Cite This Study

Suda et al. (2025) studied this question.

synapsesocial.com/papers/69449a922f0218eca950877e https://doi.org/10.1158/2767-9764.30908594

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S4 from Low <i>OLFM1</i> and <i>BMP6</i> Expression Predicts Recurrence in Early-Stage Nonsquamous NSCLC with Pure Solid Tumor Appearance2025
2Supplementary Figure S11 from Low <i>OLFM1</i> and <i>BMP6</i> Expression Predicts Recurrence in Early-Stage Nonsquamous NSCLC with Pure Solid Tumor Appearance2025
3Supplementary Figure S9 from Low <i>OLFM1</i> and <i>BMP6</i> Expression Predicts Recurrence in Early-Stage Nonsquamous NSCLC with Pure Solid Tumor Appearance2025
4Supplementary Figure S6 from Low <i>OLFM1</i> and <i>BMP6</i> Expression Predicts Recurrence in Early-Stage Nonsquamous NSCLC with Pure Solid Tumor Appearance2025
5Supplementary Figure S5 from Low <i>OLFM1</i> and <i>BMP6</i> Expression Predicts Recurrence in Early-Stage Nonsquamous NSCLC with Pure Solid Tumor Appearance2025

Supplementary Figure S10 from Low <i>OLFM1</i> and <i>BMP6</i> Expression Predicts Recurrence in Early-Stage Nonsquamous NSCLC with Pure Solid Tumor Appearance2025
Supplementary Figure S1 from Low <i>OLFM1</i> and <i>BMP6</i> Expression Predicts Recurrence in Early-Stage Nonsquamous NSCLC with Pure Solid Tumor Appearance2025
Supplementary Figure S8 from Low <i>OLFM1</i> and <i>BMP6</i> Expression Predicts Recurrence in Early-Stage Nonsquamous NSCLC with Pure Solid Tumor Appearance2025