Bacteriological Profile and Antimicrobial Susceptibility Patterns in Acute Bacterial Meningitis Among Children
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Overview
Descriptive study reveals bacterial pathogens and their antimicrobial susceptibility patterns in pediatric meningitis cases, indicating the need for tailored treatment.
Key Points
To identify the bacterial pathogens and their antibiotic sensitivity in pediatric meningitis cases.
Descriptive cross-sectional study conducted in Lahore
Cerebrospinal fluid samples were processed using standard microbiological techniques
Pathogens identified by Gram staining, colony morphology, and biochemical tests
Antimicrobial susceptibility tested using the Kirby-Bauer disc diffusion method
Minimum inhibitory concentrations were determined using the E-test technique.
21.8% of suspected cases were confirmed as bacterial meningitis
Streptococcal species were predominant among Gram-positive organisms
E. coli and other lactose-fermenters dominated among Gram-negative isolates
Gram-positive bacteria showed high sensitivity to vancomycin and linezolid
Lactose fermenters had low sensitivity to beta-lactams and quinolones.