What does this research mean for the field?

Left atrial myxoma can present with diverse clinical manifestations across different age groups, and one patient died from postoperative sepsis following surgical excision. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To present two distinct cases of left atrial myxoma across different age groups and highlight their diverse clinical presentations, imaging, and histopathological findings.

January 10, 2026Open Access

Left Atrial Myxoma: An Enigma in Itself – Two Case Reports

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Key result

Left atrial myxoma excision shows mixed case outcomes including one death from postoperative sepsis.

Why the study?

Cardiac myxomas are rare primary cardiac tumours with variable clinical presentation.

Population

Two patients with left atrial myxoma

Design

Two case reports

Authors

FCFiza ChopraMaharishi Markandeshwar University, Mullana NSNeha SinghMaharishi Markandeshwar University, Mullana RKRupinder KaurMaharishi Markandeshwar University, Mullana

Discussion

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Implication

Postoperative sepsis risk persists after left atrial myxoma resection; leaves open age-specific predictors and prevention strategies.

Key Points

To present two distinct cases of left atrial myxoma across different age groups and highlight their diverse clinical presentations, imaging, and histopathological findings.
Evaluated two patients (a 40-year-old female and a 16-year-old male) using routine laboratory tests, electrocardiography, transthoracic echocardiography (TTE), and contrast-enhanced computed tomography (CECT) of the chest.
Performed surgical excision of the intracardiac masses followed by gross and microscopic histopathological examination.
TTE and CECT chest detected left atrial masses in both patients (a 3.6 × 3.0 cm mass attached to the anterior mitral leaflet in Case 1).
Histopathology confirmed cardiac myxoma in both cases, showing nests and cords of lepidic cells within a myxoid stroma with hemosiderin-laden macrophages.
The 40-year-old female developed postoperative sepsis on day two and expired, whereas the 16-year-old male recovered uneventfully.

Structured PICO

Population

2 patients with left atrial myxoma (a 40-year-old female presenting with dyspnoea and syncopal episodes, and a 16-year-old male presenting with atypical chest pain and a prior neurological event).

Intervention

Surgical excision

Left atrial myxomas can present with diverse clinical manifestations across a broad age spectrum, highlighting the need for timely imaging and surgical intervention.

Cite This Study

Chopra et al. (2026) studied this question. One patient with left atrial myxoma died from postoperative sepsis, while the 16-year-old male recovered uneventfully after surgical excision.

synapsesocial.com/papers/696321d891e05aa366cb81de https://doi.org/10.21276/apalm.3724

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Left Atrial Myxoma: An Enigma in Itself – Two Case Reports

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Left Atrial Myxoma: An Enigma in Itself – Two Case Reports

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider