The Modified Four-Factor Functional Frailty Index (mFF-4) showed higher predictive accuracy for postoperative complications compared to the mFI-5, with ORs >2.0 for high frailty.
Does the mFF-4 frailty index improve prediction of 30-day postoperative outcomes compared to the mFI-5 in patients >75 years undergoing colorectal surgery?
The mFF-4 frailty index, which focuses on functional capabilities, is more predictive of 30-day postoperative complications than the mFI-5 in older patients undergoing colorectal surgery.
Absolute Event Rate: 0% vs 0%
BACKGROUND: Since its introduction, the Modified Five-Factor Frailty Index (mFI-5) has been widely applied across subspecialties using the National Surgical Quality Improvement Program (NSQIP) database. Although the mFI-5 index is predictive, it predominantly focuses on comorbidities and does not represent functional frailty aspects. We sought to apply the new Modified Four-Factor Functional Frailty Index (mFF-4) to a colorectal population. METHODS: This retrospective study using NSQIP 2021-2022 includes patients >75 years of age who underwent colon and rectal surgery. The mFF-4 frailty index is scored by adding one point for each present variable including history of falls, dementia, poor nutritional status (body mass index 2) and higher AUCs (most >0.7) than the mFI-5 for predicting mortality, pneumonia, ventilator use >48 hours, delirium, length of stay >30 days, and nonhome discharge destination. For these complications, patients with high frailty (mFF-4=2+) had statistically significant odds ratios >2.0. CONCLUSION: This new frailty index, focused on functional capabilities, is more encompassing of phenotypical frailty and is more predictive than the mFI-5. This new scale will help risk-stratify our aging colorectal population.
Agathis et al. (Fri,) reported a other. The Modified Four-Factor Functional Frailty Index (mFF-4) showed higher predictive accuracy for postoperative complications compared to the mFI-5, with ORs >2.0 for high frailty.