Key result
Fetal pulmonary-to-aortic valve diameter ratio reliably predicts CoA, showing early signs in ~80% of confirmed cases.
Why the study?
Aortic coarctation has one of the lowest detection rates among congenital heart diseases, and improving diagnostic rates enables centralization of high-risk cases to reduce neonatal morbidity and mortality.
Do specific fetal echocardiographic features, such as the PV/AV diameter ratio and aortic isthmus z-score, predict the postnatal development of aortic coarctation?
Population
128 patients meeting inclusion criteria among 184 cases with prevalent right-sided heart sections
Comparison
Various fetal echocardiographic parameters for predicting postnatal aortic coarctation
Design
Retrospective analysis
Authors
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Supports PV/AV ratio for fetal CoA screening; leaves open prospective validation before practice change.
Do specific fetal echocardiographic features, such as the PV/AV diameter ratio and aortic isthmus z-score, predict the postnatal development of aortic coarctation?
Fetal echocardiographic parameters, specifically the PV/AV diameter ratio and aortic isthmus z-score, are reliable predictors for the postnatal development of aortic coarctation.
Bernardi et al. (2026) studied this question. The ratio of pulmonary to aortic valve diameters was the most reliable echocardiographic parameter for predicting aortic coarctation, with 80% of confirmed cases showing early signs.
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