In 75 patients with obstructive hypertrophic cardiomyopathy, there was a poor correlation between physician-assessed symptom burden and objective exercise capacity measures.
Does physician-assessed symptom burden correlate with objective measures of exercise capacity and patient-reported measures in patients with obstructive hypertrophic cardiomyopathy?
There is a poor correlation between physician-assessed symptom burden, objective exercise capacity, and patient-reported measures in patients with obstructive hypertrophic cardiomyopathy, highlighting the need for comprehensive assessment.
Absolute Event Rate: 0% vs 0%
INTRODUCTION: In obstructive hypertrophic cardiomyopathy (oHCM), peak oxygen consumption (pVO METHODS: Consecutive patients with oHCM undergoing CPET and KCCQ at two HCM-centers. Correlations were assessed between continuous measures and according to subgroups of pVO RESULTS: Clinical evaluation and CPET were performed in 75 patients: 59 ± 13 years, resting LVOT gradient 81 ± 29 mmHg, pVO CONCLUSION: Poor correlation and substantial differences were observed between physician assessed symptom burden, objective measures of exercise capacity, and patient-reported measures. These findings provide insight for considered in the context of clinical management decisions and clinical trials in oHCM.
Bjerregaard et al. (Thu,) reported a other. In 75 patients with obstructive hypertrophic cardiomyopathy, there was a poor correlation between physician-assessed symptom burden and objective exercise capacity measures.