Young chronic e-cigarette users displayed abnormal cardiopulmonary responses during exercise, with blunted pulmonary diffusing capacity compared to controls.
Does chronic e-cigarette use alter cardiopulmonary function and pulmonary diffusing capacity during exercise in young, otherwise healthy adults?
Young, healthy chronic e-cigarette users without a smoking history demonstrate subclinical cardiopulmonary abnormalities during exercise despite normal resting pulmonary function.
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BACKGROUND: The prevalence of e-cigarette use is increasing, and e-cigarette users with no history of tobacco smoking report greater respiratory symptoms. Traditional evaluation of resting pulmonary function may fail to detect subclinical abnormalities. RESEARCH QUESTION: To what extent do young, otherwise healthy chronic e-cigarette users with no tobacco smoking history exhibit altered cardiopulmonary function during exercise, and altered recruitment of pulmonary diffusing capacity (DL STUDY DESIGN AND METHODS: 20 chronic e-cigarette users (mean age: 23±4 years) with no tobacco smoking history and 20 age-, height-, and sex-matched controls underwent a pulmonary function test and cardiopulmonary exercise test. Key outcomes included exercise capacity (V˙O RESULTS: Both groups presented with normal pulmonary function (all p INTERPRETATION: Young, otherwise healthy chronic e-cigarette users exhibit evidence of abnormal cardiopulmonary responses to exercise, and blunted DL
Williams et al. (Thu,) reported a other. Young chronic e-cigarette users displayed abnormal cardiopulmonary responses during exercise, with blunted pulmonary diffusing capacity compared to controls.
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