Cardiorespiratory fitness was significantly lower in young patients newly diagnosed with MS compared to normative values (p < 0.001).
Is cardiorespiratory fitness impaired in young, newly diagnosed patients with multiple sclerosis compared to normative values?
Young patients with newly diagnosed multiple sclerosis already exhibit substantially reduced cardiorespiratory fitness compared to normative values.
Absolute Event Rate: 0% vs 0%
BACKGROUND: Cardiorespiratory fitness (CRF) is impaired in patients with multiple sclerosis (MS) regardless of age, but evidence is limited among young and newly diagnosed patients. The aim of the study is to assess CRF using a maximal exercise test on a treadmill and to examine the relationships between CRF, physical activity level, fatigue, depression, and quality of life (QoL) in young patients newly diagnosed with MS. METHODS: This cross-sectional study analyzed baseline data from a sample of 43 patients with MS who completed a maximal exercise test on a treadmill, measurement of body composition, and answered the Beck Depression Inventory second edition, modified Fatigue Impact Scale, and 36-item Short Form Survey QoL. RESULTS: CRF was significantly lower among patients newly diagnosed with MS (aged 20-45 years) compared to normative values (paired Wilcoxon test, p < 0.001). The median absolute differences between normative values and patients' maximal oxygen uptake (VO CONCLUSION: Young patients with newly diagnosed MS already exhibit substantially reduced CRF compared with normative values. Lower VO
Adamec et al. (Mon,) reported a other. Cardiorespiratory fitness was significantly lower in young patients newly diagnosed with MS compared to normative values (p < 0.001).
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