The authors highlight the need for comprehensive prospective examinations in patients with congenital muscular dystrophies based on a recent cross-sectional study.
We read with interest the article by Basu et al on a cross-sectional study of the clinical presentation and genetic predisposition of 42 patients with congenital muscular dystrophy (CMD), de fi ned as the onset of muscle weakness before learning to walk. 1 The most common CMD types were COL-6-associated CMD, LAMA2-associated CMD, LMNA-associated CMD, and alpha-dystroglycanopathy. 1 Of the 33 patients whose motor and cognitive abilities were assessed, 19 were able to walk independently. 1 Motor impairments were severe in all patients, but most pronounced in those with alpha-dystroglycanopathy. 1 The study is promising, but some points warrant further discussion.
Josef Finsterer (Wed,) studied this question.
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