Low-dose alteplase reduced in-hospital mortality without increasing major bleeding risk in patients with intermediate-high-risk pulmonary embolism compared to heparin.
Does low-dose alteplase reduce in-hospital mortality and hemodynamic decompensation in patients with acute intermediate-high-risk pulmonary embolism compared to anticoagulation alone?
Low-dose alteplase added to anticoagulation in intermediate-high-risk pulmonary embolism significantly reduces in-hospital mortality and hemodynamic decompensation without increasing major bleeding compared to anticoagulation alone.
Absolute Event Rate: 0% vs 0%
Among the patients with acute intermediate-high-risk PE, low dose alteplase may be preferred safely without increasing the risk of major bleeding and reduced in-hospital mortality compared to heparin.
YÜKSEL et al. (Tue,) reported a other. Low-dose alteplase reduced in-hospital mortality without increasing major bleeding risk in patients with intermediate-high-risk pulmonary embolism compared to heparin.