What question did this study set out to answer?

To evaluate the incidence of cardiovascular diseases and identify independent risk predictors for cardiovascular comorbidities among stable COPD patients.

January 10, 2026Egyptian Journal of BronchologyOpen Access

Screening of cardiovascular disorders among stable COPD patients

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Key result

Stable COPD links to prevalent CVD in ~30% of patients alongside frequent PH.

Why the study?

Cardiovascular disorder is an important comorbidity in COPD, but the incidence of CVD and its risk factors among stable COPD patients required evaluation.

Key Points

To evaluate the incidence of cardiovascular diseases and identify independent risk predictors for cardiovascular comorbidities among stable COPD patients.
Conducted an observational cross-sectional study of 100 stable COPD patients attending an outpatient chest clinic in Egypt between October 2024 and May 2025.
Assessed patients using spirometry, GOLD ABE assessment, pulse oximetry, laboratory tests, chest imaging, ultrasonography, electrocardiography, and echocardiography after excluding known cardiovascular and metabolic disorders.
Performed logistic regression analysis to identify independent risk predictors for newly diagnosed cardiovascular diseases.
Among the evaluated patients, 74% presented with cardiovascular risk factors and 30% had cardiovascular diseases, including ischemic heart disease (22%), atrial fibrillation (8%), heart failure (5%), and peripheral artery disease (2%).
COPD-related cardiovascular complications were detected, comprising pulmonary hypertension in 44% and cor pulmonale in 8% of patients.
Independent risk predictors for cardiovascular diseases were forced vital capacity actual value (OR: 4.607, 95% CI: 1.459–14.548), PaCO₂ (OR: 0.835, 95% CI: 0.744–0.937), and dyslipidemia (OR: 5.660, 95% CI: 1.277–25.081).

Structured PICO

Population

100 stable COPD patients >40 years old without previously diagnosed cardiovascular diseases (IHD, HF, arrhythmia, cerebrovascular, PAD, valvular, pericardial, congenital), metabolic syndrome, or BMI ≥30. Mean age 64.9 years, 85% male, based in Egypt.

Outcome

Incidence of cardiovascular diseases among stable COPD patients

A high incidence of undiagnosed cardiovascular diseases (30%) exists among stable COPD patients, highlighting the need for routine cardiovascular screening in this population.

Discussion

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Implication

Supports CVD vigilance in stable COPD; leaves open whether screening improves outcomes.

Cite This Study

Elkholy et al. (2025) studied this question. In stable COPD patients, 30% had cardiovascular diseases, with 74% showing cardiovascular risk factors and pulmonary hypertension present in 44%.

synapsesocial.com/papers/6963223291e05aa366cb8ca3 https://doi.org/10.1186/s43168-025-00504-0

Topics

Heart failure Persistent AF management HFrEF treatment Atrial fibrillation

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Screening of cardiovascular disorders among stable COPD patients

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Screening of cardiovascular disorders among stable COPD patients

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

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