CoaguChek devices showed 86.1% of INR values within 0.4 INR units of plasma INR reference, indicating strong correlation for warfarin management.
Do point-of-care INR devices (Vantus and CoaguChek XS) provide accurate INR measurements compared to a plasma reference in warfarin-treated patients?
Bluetooth-enabled point-of-care INR devices (Vantus and CoaguChek) demonstrate strong correlation with plasma INR references, supporting their use for remote warfarin management.
Absolute Event Rate: 0% vs 0%
OBJECTIVE: Systems employing point-of-care (POC) INR monitoring with patient self-testing require test accuracy, data integrity, patient compliance, and prompt two-way communication for high quality warfarin management. With a goal of validating a POC Bluetooth capable device for prompt INR transfer to electronic medical record, two POC INR devices were compared against an internal plasma INR reference. METHODS: A multicenter study (February 14, 2023 - August 29, 2023) comparing concordance of two commercially available POC devices, Vantus and CoaguChek XS (Pro and Plus), against a plasma INR reference, was pursued among warfarin treated patients. Appropriateness of dosing decisions were assessed for each device. RESULTS: Across three Mayo Clinic sites, 151 warfarin treated patients agreed to participate. Atrial fibrillation (41.7 %), venous thromboembolism (33.1 %) and heart valve prosthesis (19.9 %) were common indications with target INR range 2.0-3.0 in 89 %. For the CoaguChek devices, 86.1 % of values fell within 0.4 INR units compared with plasma INR referent (CoaguChek - plasma INR correlation R CONCLUSIONS: Compared to a plasma referent, INR values obtained from the CoaguChek and Vantus devices exhibited strong correlation with plasma INR values without systemic bias.
McBane et al. (Mon,) reported a other. CoaguChek devices showed 86.1% of INR values within 0.4 INR units of plasma INR reference, indicating strong correlation for warfarin management.