A 38-year-old recreational athlete with hypertrophic cardiomyopathy was assessed, yielding a 5.73% five-year risk of sudden cardiac death, leading to ICD implantation.
Multimodal imaging, genetic testing, and guideline-based risk stratification can effectively guide individualized management and safe recreational sports participation in athletes with hypertrophic cardiomyopathy.
Absolute Event Rate: 0% vs 0%
Abstract Background Sports participation in patients with inherited cardiac conditions remains a major challenge, particularly when balancing arrhythmic risk against quality of life. Case Summary A case of a 38-year-old recreational athlete diagnosed with hypertrophic cardiomyopathy (HCM) is described. A comprehensive assessment was performed, including ECG, echocardiography, exercise stress testing, Holter monitoring, and cardiac magnetic resonance (CMR), which revealed asymmetric non-obstructive HCM with extensive late gadolinium enhancement. Genetic testing identified two missense variants in MYBPC3, one of which was reclassified as likely pathogenic. Risk stratification using ESC and AHA/ACC calculators demonstrated a 5.73% five-year risk of sudden cardiac death (SCD). A subcutaneous implantable cardioverter-defibrillator (ICD) was implanted after a shared decision-making process, allowing the patient to continue recreational sport while avoiding competitive athletics. Discussion This case highlights the value of multimodal imaging, genetic testing, and guideline-based SCD risk stratification in guiding individualized management of athletes with HCM.
Gomez et al. (Sat,) reported a other. A 38-year-old recreational athlete with hypertrophic cardiomyopathy was assessed, yielding a 5.73% five-year risk of sudden cardiac death, leading to ICD implantation.