What question did this study set out to answer?

To analyze similarities and differences in eye movement patterns across various mental disorders, particularly PTSD.

January 14, 2026S S Korsakov Journal of Neurology and Psychiatry0 citations

Comparative Analysis of Eye Movement Patterns in Patients with Posttraumatic Stress Disorder and Other Mental Disorders: An Analytical Review of the Literature

KSK.Yu. ShelepinFederal Medical Research Centre for Psychiatry and Narcology ESE.Yu. ShelepinPavlov Institute of Physiology of the Russian Academy of Sciences KSK.A. SkuratovaPavlov Institute of Physiology of the Russian Academy of Sciences

Key Points

To analyze similarities and differences in eye movement patterns across various mental disorders, particularly PTSD.
Literature review of global studies on eye movement patterns in mental disorders.
Comparison of oculomotor biomarkers among PTSD, depression, bipolar disorder, OCD, GAD, personality disorders, and schizophrenia.
Analysis focused on oculomotor responses and inhibitory control.
Identified common oculomotor responses associated with impaired attention control in mental disorders.
Noted pronounced amygdala hyperactivity particularly in PTSD and GAD patients.
Unique eye movement patterns were observed for each mental disorder.

Abstract

In a scientific review, global studies on this issue, covering various nosological groups, were analyzed to determine the similarities and differences in oculomotor biomarkers of mental disorders: posttraumatic stress disorder (PTSD), depressive disorder, bipolar disorder, obsessive-compulsive disorder, generalized anxiety disorder (GAD), personality disorders, and schizophrenia. The analysis showed common features of oculomotor responses associated with impaired inhibitory control of attention processes and amygdala hyperactivity, most pronounced in patients with PTSD and GAD, as well as unique eye movement patterns for each disorder.

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