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January 14, 2026Open Forum Infectious DiseasesOpen Access

P-996. Revamping Antimicrobial Stewardship at a Community Safety-Net Hospital: A Tiered, Physician- and Pharmacy-Led model

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Authors

MVMaria Rosa VelasquezNew York City Health and Hospitals CorporationALA. LlosaMetropolitan Hospital CenterHHHali HoMetropolitan Hospital Center

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Implication

Retrospective analysis shows improved antimicrobial stewardship compliance and susceptibility of pathogens in a community hospital.

Key Points

  • This study aims to evaluate the impact of a structured antimicrobial stewardship program on antibiotic effectiveness and local susceptibility patterns.
  • Retrospective analysis of yearly antibiograms from 7 NYCHHC facilities.
  • Measured ASP compliance as the proportion of accepted interventions.
  • Conducted intra- and inter-institutional comparisons of susceptibility rates using statistical tests.
  • ASP compliance improved from 82% in 2022 to 92.1% in 2024.
  • Positive trends in susceptibility for Enterococcus faecium, Escherichia coli, and Pseudomonas aeruginosa.
  • E. faecium vancomycin susceptibility increased from 28% to 75%, showing statistical significance.

Cite This Study

Velasquez et al. (2026) studied this question.

synapsesocial.com/papers/6966f2fb13bf7a6f02c005dfhttps://doi.org/10.1093/ofid/ofaf695.1195
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1P-940. Is anyone listening? Stewardship Implementation in a Large Health System: Successes and Barriers2026
  2. 2P-885. Eight Years In, Still Going Strong: A Single-Center ASP’s Sustained Success in Optimizing and Reducing Antibiotic Use2026
  3. 3Impact of an Antimicrobial Stewardship Program on Antibiotic Consumption, Bacterial Susceptibility, and Costs in a High-Complexity Public Hospital2026 · 2 citations
  4. 4Combating Antimicrobial Resistance: A Pharmacist-Led PDCA Stewardship Program in a Tertiary Hospital2026 · 1 citations
  5. 5P-997. Successful Implementation of an Infectious Disease-Led Non-Restrictive Antimicrobial Stewardship Program in a Peruvian Hospital2026