What question did this study set out to answer?

This research aims to provide an overview of ongoing clinical trials focusing on minimal residual disease in colorectal cancer.

Minimal residual disease (MRD) trials in colorectal cancer (CRC): An overview of a heterogeneous field.

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Clinical trials assess targeted therapy and adjuvant therapy for minimal residual disease in colorectal cancer, suggesting new treatment strategies.

This research aims to provide an overview of ongoing clinical trials focusing on minimal residual disease in colorectal cancer.
Screening of Clinicaltrials.gov for trials on colorectal cancer with keywords MRD and minimal residual disease.
Data collection on geographical region, trial phase, tumor stage, ctDNA requirements, and therapy types.
Identification of trial types and primary endpoints among MRD trials.
41 MRD trials identified across various regions, with 23 currently recruiting.
Diverse tumor stages included, emphasizing heterogeneity in trial designs and endpoints.
Targeted therapy and innovative approaches are increasingly explored alongside traditional adjuvant therapies.

Österlund et al. (2026) studied this question.

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Clinical trials assess targeted therapy and adjuvant therapy for minimal residual disease in colorectal cancer, suggesting new treatment strategies.