The research aims to evaluate the effects of EgM123 on Th1 and Th2 immune responses in a colitis model.
Utilized a dextran sodium sulfate-induced colitis model in mice
Administered EgM123 to modulate immune responses
Monitored inflammatory markers and immune cell profiles
EgM123 inhibited the Th1 response
EgM123 induced a Th2 immune response
Immunotherapy with EgM123 suggested potential benefits in reducing colitis symptoms
Abstract
EgM123 may alleviate colitis by inhibiting the Th1 response and inducing Th2 immunity. Immunotherapy with EgM123 may represent a strategy to modulate the inflammatory processes involved in IBD.